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3'-phosphoadenosine-5'-phosphosulfate (PAPS, 3-phosphoadenylyl sulfate)

Function: - universal sulfuryl donor for sulfation events that take place in the Golgi - activated sulfate donor used by sulfotransferase. - formed by from ATP & sulfate in a 2 step reaction catalyzed by sulfurylase kinase 1 - adenosine 5' phosphosulfate is an intermediate - PAPS is transported from cytosol to GOLGI by SLC35B2 & secondarily SLC35B3

Related

bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; PAPS synthase 1; PAPSS 1; sulfurylase kinase 1; SK 1; SK1; includes: sulfate adenylyltransferase; ATP-sulfurylase; sulfate adenylate transferase; SAT; includes: adenylyl-sulfate kinase; 3'-phosphoadenosine-5'-phosphosulfate synthase; APS kinase; adenosine-5'-phosphosulfate 3'-phosphotransferase; adenylylsulfate 3'-phosphotransferase (PAPSS1, ATPSK1, PAPSS)

General

adenosine 5' phosphosulfate (APS, adenylyl sulfate)

Properties

COMPARTMENT: golgi

Database Correlations

PUBCHEM correlations

References

UniProt :accession O43252