Search
3'-phosphoadenosine-5'-phosphosulfate (PAPS, 3-phosphoadenylyl sulfate)
Function:
- universal sulfuryl donor for sulfation events that take place in the Golgi
- activated sulfate donor used by sulfotransferase.
- formed by from ATP & sulfate in a 2 step reaction catalyzed by sulfurylase kinase 1
- adenosine 5' phosphosulfate is an intermediate
- PAPS is transported from cytosol to GOLGI by SLC35B2 & secondarily SLC35B3
Related
bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1; PAPS synthase 1; PAPSS 1; sulfurylase kinase 1; SK 1; SK1; includes: sulfate adenylyltransferase; ATP-sulfurylase; sulfate adenylate transferase; SAT; includes: adenylyl-sulfate kinase; 3'-phosphoadenosine-5'-phosphosulfate synthase; APS kinase; adenosine-5'-phosphosulfate 3'-phosphotransferase; adenylylsulfate 3'-phosphotransferase (PAPSS1, ATPSK1, PAPSS)
General
adenosine 5' phosphosulfate (APS, adenylyl sulfate)
Properties
COMPARTMENT: golgi
Database Correlations
PUBCHEM correlations
References
UniProt :accession O43252